2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

TCR V β 11

Also called TCRBV11S1

V β 11 is the human variable β 11 chain of the T cell receptor. Two V β 11 sequences are described, PL3.12 and PH15. These sequences differ only in their leader sequence and therefore lead to the same mature protein. An invariant V α 24/V β 11 T cell receptor is expressed in all individuals by clonal expanded CD4– CD8– T cells, reactive to bacterial antigens. This unique lymphocyte population restricted by the CD1d molecule recognition has been identified as the natural killer T (NKT) cells. V β 11 is expressed by 0.4% to 0.9% of peripheral CD3+ cells in normal blood. This sequence is also referred to as TRBV25-1 (based on the IMGT gene nomenclature).

Tri Vbeta 11 Cell line.

Clone: C21 (IgG2a Mouse) The C21 recognizesthe gene productof PL3.12and PH15 sequences. Thespecificityof this antibodyhas been confirmedat the First HumanTcR Monoclonal Antibody Workshop in San Francisco in 1995.

Form

Format

Part#

Status

Line

Quality Standard

Size

FITC

IM1586 IM2290 A66905

1 mL 1 mL

Liquid Liquid Liquid

ASR ASR ASR

IOTest IOTest IOTest

cGMP cGMP cGMP

PE

APC

0.5 mL

TCR V β 12

Also called TCRBV12S1

V β 12 is a family of the T cell receptor. It is expressed by 1.1% to 1.9% of peripheral CD3 + cells in normal blood. This sequence is also referred to as TRBV10-3 (based on the IMGT gene nomenclature).

NT12.2.1 Cell line.

Form (PL4.2 sequence) and other recently described V β 12 genes (HT96 sequence) has not been found but cannot be formally excluded. Part# Format Size Status Line Clone: VER2.32.1 (IgG2a Mouse) The VER2.32.1monoclonalantibodyrecognizesHBP54identicalto PH27sequenceoftenreferredto as V β

12.2. The reactivityof the othermembersof this family

Quality Standard

FITC

IM1587 IM2291

1 mL 1 mL

Liquid Liquid

ASR ASR

IOTest IOTest

cGMP cGMP

PE

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 133 Outside US Flow Cytometry Catalog