2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

Human Interferon- γ (IFN- γ ) is a 20-25 kDa (monomer) pleiotrophic cytokine that is produced by activated T cells and NK cells and is involved in the regulation of almost all immune and inflammatory responses. IFN- γ is involved in the activation, growth and differentiation of T cells, B cells, macrophages, NK cells as well as other cell types. IFN- γ enhances MHC expression on antigen-presenting cells including epithelial, endothelial and connective tissue cell and monocytes cell lines. It also has weak antiviral activity and acts as a macrophage-activating factor (MAF) for tumor cytotoxicity leading to anti-tumor effects. IFN- γ

Activated peripheral blood lymphocytes (PBL).

Clone: 45.15 (IgG1 Mouse) The FITC- and PE-conjugatedforms of the 45.15 antibodyare optimizedfor flow cytometricdetectionof intracellularIFN- γ mononuclear cells (PBMC) after permeabilization with IntraPrep permeabilization reagent. 45.15 cross reacts with: Indian Rhesus.

in stimulatedperipheralblood

Form

Format

Part#

Status

Line

Quality Standard

Size

PB

B46034 IM2716U IM2717U

0.5 mL

Liquid Liquid Liquid

ASR ASR ASR

IOTest IOTest IOTest

cGMP cGMP cGMP

FITC

2 mL 2 mL

PE

IgD

IgD, a member of the immunoglobulin (Ig) family, is expressed in naïve B cells. It exists in a transmembrane and a soluble form. IgD is, together with IgM, the first antibody isotypes expressed during B cell ontogeny. Bone marrow B cell precursors acquire surface IgM after assembling heavy (H) and light (L) chain variable region exons from prototypic variable (V), diversity (D) and joining (J) gene segments through an antigen-independent process. After leaving the bone marrow to colonize secondary lymphoid organs, B cells acquire surface IgD of the same specificity as surface IgM through alternative splicing of a pre-messenger RNA comprising V(D)J and both heavy chain constant μ (C μ ) and C δ exons.

Pre-washed lysed normal whole blood sample.

Clone: IA6-2 (IgG2a Mouse) The IA6-2 monoclonal antibody binds specifically to the heavy chain of human IgD.

Form

Format

Part#

Status

Line

Quality Standard

Size

FITC

B30652 B30653 B30651

50 tests 50 tests 50 tests

Liquid Liquid Liquid

RUO RUO RUO

IOTest IOTest IOTest

cGMP cGMP cGMP

PE

APC

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 117 Outside US Flow Cytometry Catalog