2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

HLA-DR

The human major histocompatibility complex (MHC), also called human leucocyte antigens (HLA), is composed of three groups of molecules designated MHC class I, class II and class III. The MHC class II genomic region, or HLA-D region, contains the genes encoding HLA-DR, -DQ and -DP antigens. The MHC class II molecules are built by the non-covalent association of α / β heterodimers. Both heavy ( α ) and light ( β ) chains span the cell membrane. They have molecular weights of 31-33 kDa and 26-29 kDa respectively. HLA-DR molecules are found on antigen-presenting cells (APC), i.e. dendritic cells, B lymphocytes, monocytes, macrophages, Langerhans cells and thymic epithelial cells. They are also expressed on activated T cells, but not on granulocytes, platelets, or red blood cells. Resting T cells or endothelial cells that do not normally express these molecules can be induced to express them. HLA-DR is also expressed on some hematopoietic progenitor cells at different stages of differentiation.

Lysed normal whole blood sample.

Clone: B8.12.2 (IgG2b Mouse) HLA-DRantibodiesare specificto nonpolymorphicdeterminantsof humanHLAclassII DRmoleculeswhichare constitutedof α and β polypeptidesof 34 and29 kDa respectively. B8.12.2 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Olive Baboon, Common Marmoset, Cotton-topped Tamarin, Squirrel Monkey.

Form

Format

Part#

Status

Line

Quality Standard

Size

FITC

IM0463U IM0464U

2 mL 2 mL

Liquid Liquid

ASR ASR

IOTest IOTest

cGMP cGMP

PE

Clone: Immu-357 (IgG1 Mouse) Immu-357 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Hamadyras Baboon, Olive Baboon, Capuchin Monkey, Cotton-topped Tamarin.

Form

Format

Part#

Status

Line

Quality Standard

Size

PB PB

B36291 A74781 B00070 B96758 IM1638U IM1639U B92438 IM3636 A07793 IM2659U B20024 B49180 A40579 IM3635 B42021 IM1639

50 tests 0.5 mL 0.5 mL 100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

CE/IVD

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

98/79/EC

ASR ASR

cGMP cGMP

KrO FITC FITC

CE/IVD

98/79/EC

2 mL

ASR

cGMP

PE PE

100 tests

CE/IVD

98/79/EC

2 mL

ASR

cGMP

ECD ECD PC5 PC5 PC7 PC7 APC

100 tests

CE/IVD

98/79/EC

1 mL

ASR

cGMP

100 tests

CE/IVD

98/79/EC

1 mL

ASR ASR

cGMP cGMP

PC5.5

0.5 mL 50 tests 0.5 mL

CE/IVD

98/79/EC

ASR ASR ASR

cGMP cGMP cGMP

1 mL

APC-A750

0.5 mL

HLA-DR, DP, DQ

The recognized epitope is specific to a non-polymorphic HLA class II (DR, DP, DQ) Ia antigen constituted of α and β polypeptides of 34 and 29 kDa respectively. This antigen is expressed on monocytes, macrophages, B lymphocytes and activated T lymphocytes.

Clone: 9-49 (IgG2a Mouse) 9-49 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Hamadyras Baboon, Olive Baboon, Capuchin Monkey, Squirrel Monkey.

Form

Format

Part#

Status

Line

Quality Standard

Size

RD1

6604366

0.5 mL

Liquid

ASR

CYTO - STAT

cGMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 116 Outside US Flow Cytometry Catalog