2020 Outside US Flow Cytometry Catalog

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Single-Color Conjugated Antibodies

CD326 also known as EpCAM (Epithelial Cell Adhesion Molecule) is a 40 kDA type I transmembrane glycoprotein expressed at the cell surface of a variety of epithelial cells. CD326 is a hemophilic Ca2+ independent cell-cell adhesion molecule which plays a major role in intercellular adhesion. Additionally it has been described to play an important role in cell signaling, proliferation, differentiation and maintenance of organ morphology. In the field of oncology, CD326 is a key marker for the isolation and identification of circulating tumor cells. CD326 ( EpCAM )

HT29 cell line.

Clone: VU1D9 (IgG1 Mouse) The monoclonal antibody VU1D9 recognizes an epitope within EGF like domain I of CD326.

Form

Format

Part#

Status

Line

Quality Standard

Size

APC

B90408

0.5 mL

Liquid

ASR

IOTest

cGMP

NEW

The p75 adhesion inhibitory receptor molecule 1 (p75/AIRM1), also known as Siglec-7, belongs to the CD33-related Siglec subgroup. p75 AIRM1 is a type I transmembrane glycoprotein, belonging to the immunoglobulin superfamily (Ig-SF) and sharing sequence homology with the sialic acids binding Ig-like lectins. The extracellular domain of the p75/AIRM1 molecule is relatively highly N-glycosylated and displays three extracellular Ig-like domains. The cytoplasmic tail is characterized by a classical ITIM motif responsible for the inhibitory functions of this receptor. p75 AIRM1 is expressed on activated and resting NK cells, monocytes, some chronic (CML) and acute myeloid leukemias (AML). p75 AIRM1 is a novel, HLA independent, inhibitory receptor that may play a relevant role in the negative regulation of human NK cell functions. CD328 ( p75 AIRM1 )

Lysed normal whole blood sample.

Clone: Z176 (IgG2b Mouse)